2-butyl-5-nitro-3-benzofuranyl)[4-[3-(dibutylaMino)propoxy]phenyl]

Ana amfani da shi a asibiti a cikin hyperuricemia na farko da na sakandare, musamman a cikin marasa lafiya masu fama da hyperuricemia, da kuma marasa lafiya marasa lafiya na koda, da marasa lafiya masu maimaitawa ko ciwon gout, da kuma marasa lafiya tare da hyperuricemia.An yi amfani da shi a cikin marasa lafiya tare da Gouty nephropathy don taimakawa bayyanar cututtuka da rage samuwar duwatsun uric acid na koda;gout duwatsu;ana amfani dashi a cikin cututtukan koda da uric acid.

Sabuwar maganin hana arrhythmic Atrial fibrillation (AF) cuta ce mai hatsarin gaske.Saboda tsufa na yawan jama'a, abubuwan da ke faruwa a duniya da mace-mace na fibrillation suna karuwa, kuma ya zama sabon matsalolin Kiwon Lafiyar Jama'a.Akwai marasa lafiya miliyan 2.5 da ke da fibrillation a cikin Amurka da miliyan 4.5 a cikin Tarayyar Turai.Bisa kididdigar da aka yi, yawan fibrillation a cikin mutane sama da shekaru 30 a cikin ƙasata shine 0.77%, wanda ke karuwa da shekaru, kuma maza sun fi mata (0.9%: 0.7%).Cututtukan da ke haifar da fibrillation sun haɗa da hauhawar jini, cututtukan zuciya, cututtukan zuciya na valvular, dilated cardiomyopathy, da gazawar zuciya.Babban alamar cututtuka na marasa lafiya tare da fibrillation na atrial shine rashin daidaituwa na ventricular rate, kuma kula da ƙwayar zuciya yana da wani matsayi a cikin m jiyya da kuma kula da bayyanar cututtuka.Amiodarone yana taka rawa mai kyau wajen sarrafa bugun zuciya da maido da rudani na sinus, amma illar gabobin da aka yi niyya da ke da alaka da bangaren aidin a cikin tsarinsa yana iyakance aikace-aikacensa na asibiti, kamar lalacewar huhu, thyroid, da hanta.Abubuwan da aka ambata a sama mara kyau da tsarin sa Iodin a ciki yana da alaƙa da kusanci.An samo sabon maganin antiarrhythmic Dronedarone (Dronedarone) ta hanyar gyara tsarin amiodarone.Dronedarone yana da kaddarorin electrophysiological kama da amiodarone, amma ba ya ƙunshi aidin a cikin tsarin sa, don haka zai iya guje wa mummunan illar cututtukan zuciya da ke haifar da iodine Chemicalbook.An amince da Dronedarone don tallata daga Hukumar Abinci da Magunguna ta Amurka (FDA) a cikin Yuli 2009, kuma an amince da ita don tallata a cikin Tarayyar Turai a cikin 2009. Har ila yau, shi ne sabon maganin rigakafin arrhythmic na farko da aka amince da shi a cikin Tarayyar Turai cikin shekaru 10.Dronedarone shine N-[2-butyl-3-[4-[3-dibutylamino) propoxy] phenyl] -5-benzofuranyl]-methanesulfonamide, wanda shine don rage A benzofuran wanda aka samo ta hanyar gyare-gyaren tsari na amiodarone, wanda ba haka ba ne. cardiac m dauki.Yana kawar da zarra na aidin a cikin amiodarone don rage yawan guba na thyroid da sauran gabobin;yana ƙara ƙungiyar methylsulfonyl a gefen benzofuran don rage lipophilicity, ta haka ne ya rage rabin rayuwar miyagun ƙwayoyi da kuma rage tasirin ƙwayar nama da yiwuwar maganin neurotoxicity.Dukansu nau'in 2011 na Amurka da 2010 na Turai na Jagororin Atrial Fibrillation sun ba da shawarar dronedarone don maganin fibrillation.Dronedarone yana da lafiya kuma yana da tasiri a cikin maganin ventricular rate da kuma kiyaye yawan sinus a cikin marasa lafiya daban-daban ba tare da AF mai tsanani ba.Zai iya zama magani mai mahimmanci don maye gurbin amiodarone.Dronedarone kuma na iya rage mutuwar majinyatan AF har ma da majinyatan AF masu dagewa.Sabili da haka, ana sa ran zama magani na farko ga marasa lafiya na AF ba tare da raunin zuciya mai tsanani ba.Bugu da ƙari, yin amfani da maganin rigakafi a cikin marasa lafiya na AF masu haɗari na tsakiya yana da amfani ga amfani da dronedarone.