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L-Valine

L-Valine

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CAS noSaukewa: 72-18-4

Abubuwan sinadaran: Valaciclovir Intermediates


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Amfani

Ana amfani da L-Valine azaman matsakaici na Valaciclovir.
Valacyclovir guanine analogue antiviral miyagun ƙwayoyi.Ana amfani da shi a cikin maganin asibiti na cutar ta herpes simplex da cutar ta herpes zoster a cikin cututtukan da ake daukar su ta hanyar jima'i.Wannan samfurin shine farkon acyclovir.Ana ɗaukar shi da sauri bayan gudanarwa ta baki kuma da sauri ya canza zuwa acyclovir a cikin jiki.Its antiviral sakamako ne taka acyclovir.Bayan acyclovir ya shiga cikin kwayoyin cutar herpes, yana gasa tare da deoxynucleoside don kwayar cutar thymidine deoxynucleoside kinase ko cell kinase, kuma ana amfani da miyagun ƙwayoyi a cikin phosphorylated acyclic guanosine triphosphate.A matsayin substrate na kwafin ƙwayar cuta, acyclovir yana gasa tare da deoxyguanine triphosphate don ƙwayoyin cuta DNA polymerase, wanda ke hana ƙwayoyin DNA kira kuma yana nuna tasirin antiviral.Ayyukan antiviral na wannan samfurin a cikin vivo ya fi acyclovir, kuma ma'anar jiyya na nau'in cutar ta herpes simplex I da nau'in II shine 42.91% da 30.13% fiye da acyclovir bi da bi.Hakanan yana da tasirin warkewa sosai akan cutar varicella zoster.


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